Clinical Faculty

GARY N. FOULKS, MD, FACS

Professor Emeritus, Department of Ophthalmology & Visual Sciences

CLINICAL EXPERTISE:

Cornea and External Disease, Ocular Surface Disease, Dry Eye

CONTACT INFORMATION:

301 E. Muhammad Ali Boulevard, Louisville KY 40202
Telephone: 502-852-5466 Fax: 502-852-8550
E-mail: gnfoul01@louisville.edu

EDUCATION:

CERTIFICATION:

American Board of Ophthalmology, 1977

RESEARCH INTERESTS:

My research is focused on corneal and external disease of the eye, including ocular surface disease and dry eye disease.

Dry eye disease and lid margin disease are the most common problems encountered by ophthalmologists. With the advancing age of the population and the fact that women outlive men, the prevalence of both diseases is increasing and treatment options have been limited. My research in collaboration with Douglas Borchman, PhD has provided valuable information about both dry eye disease and lid margin disease allowing us to characterize the behavior of secretions of the lid and lacrimal glands by a variety of methods of spectroscopy. This has allowed better understanding of the disease and our ability to evaluate therapies for the clinical problem

PUBLICATIONS:

(15 selected publications from 107)

1. Borchman D, Foulks GN, Yappert MC, Kakar S, Podoll N, Rychwalski P, Schwietz E: Physical Changes in Human Meibum with Age as Measured by Infrared Spectroscopy. Oph Res 2010 17;44(1):34-42. PMID: 20160464
2. Oshima Y, Sato H, Zaghloul A, Foulks GN, Yappert MC, Borchman D. Characterization of Human Meibum Lipid using Raman Spectroscopy. Curr Eye Res. 2009;34:824-35. PMID: 19895310
3. Borchman D, Foulks GN, Yappert MC, Mathews J, Leake K, Bell J: Factors affecting evaporation rates of tear film components measured in vitro.Eye Contact Lens. 2009 Jan;35(1):32-7. PMID: 19125046
4. Jiang G, Ke Y, Sun D, Li H, Ihnen M, Jumblatt MM, Foulks GN, Wang Y, Bian Y, Kaplan HJ, Shao H.A new model of experimental autoimmune keratoconjunctivitis sicca (KCS) induced in Lewis rat by the autoantigen Klk1b22. Invest Ophthalmol Vis Sci. 2009;50:2245-54. PMID: 19060269
5. Foulks GN: Treatment of dry eye disease by the non-ophthalmologist. Rheum Dis Clin North Am 2008;34:987-1000. PMID: 18984417
6. Imbert Y, Foulks GN, Brennan MD, Jumblatt MM, John G, Shah HA, Newton C, Pouranfar F, Young WW Jr.: MUC1 and estrogen receptor alpha gene polymorphisms in dry eye patients.Exp Eye Res. 2009;88:334-8. PMID18619437
7. Foulks GN: Pharmacological management of dry eye in the elderly patient. Drugs Aging. 2008;25(2):105-18. PMID 18257598
8. Foulks GN: Amniotic membrane therapy in the acute phase of toxic epidermal necrolysis. Journal of AAPOS; American Assn for Pediatric Ophthalmology and Strabismus 2007;11:531. PMID18086431
9. Foulks, Gary N. Acanthamoeba keratitis and contact lens wear: static or increasing problem?. Eye & Contact Lens: Science & Clinical Practice, 2007;33(6 Pt 2):412-4; PMID: 17975435 discussion 424-5.
10. Borchman D. Foulks GN. Yappert MC. Ho DV. Temperature-induced conformational changes in human tear lipids hydrocarbon chains. Biopolymers 2007;87(2-3):124-33. PMID:17600814
11. Foulks GN. The correlation between the tear film lipid layer and dry eye disease. Survey of Ophthalmology. 2007;52(4):369-74. PMID: 17574063
12. Lemp M, Baudouin C, Baum J, Dogru M, Foulks G, Kinoshita S, Laibson P, McCulley J, Murube J, Pfugfelder S, Rolando M, Toda I: The Definition and Classification of Dry Eye Disease: Report of the Definition and Classification Subcommittee of the International Dry Eye WorkShop (2007). The Ocular Surface 2007;5(2):75-92.
13. Tsubota K, Asbell P, Dogru M, Fonn D, Foulks G, Schaumberg D, Schein O, Watanabe H: Design and Conduct of Clinical Trials: Report of the Clinical Trials Subcommittee of the International Dry Eye WorkShop (2007). The Ocular Surface 2007;5(2):153-62.
14. Borchman D, Foulks GN, Yappert MC, Ho D: Spectroscopic Evaluation of Human Tear Lipids. Chemistry and Physics of Lipids 2007;147(2):87-102. PMID:17482588